Despite significant advancements in combating the COVID-19 pandemic, the United States continues to experience a concerning number of fatalities every week. According to the Centers for Disease Control and Prevention (CDC), an average of 350 individuals succumbed to the virus each week in April 2025 .
A new subvariant, NB.1.8.1, part of the Omicron sublineage JN.1, has been identified as a contributing factor to the recent uptick in cases . Initially causing surges in Asia, this variant is now spreading rapidly across the U.S., raising concerns among health experts about its increased transmissibility.
Factors Contributing to Ongoing Fatalities
Several elements are contributing to the sustained death toll:
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Low Vaccination Rates: Only 23% of adults aged 18 and older received the updated COVID-19 vaccine during the 2024–25 season. Among children, the rate is even lower at 13% .
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Declining Immunity: Dr. Gregory Poland, a vaccine specialist, notes that waning immunity over time increases susceptibility to infection, especially among the elderly and immunocompromised.
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High-Risk Populations: Individuals aged 75 and older are experiencing the highest death rates, with 4.66 fatalities per 100,000 people .
Public Health Response and Recommendations
Health experts emphasize the importance of:
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Vaccination: Encouraging booster shots, particularly for vulnerable populations, to enhance immunity.
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Monitoring New Variants: Continuous surveillance of emerging strains like NB.1.8.1 to inform public health strategies.
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Public Awareness: Educating the public on the ongoing risks and the importance of preventive measures.
While the U.S. has made significant strides in managing the pandemic, the persistent weekly deaths underscore the need for continued vigilance. Addressing low vaccination rates, monitoring new variants, and protecting high-risk groups remain critical components in the ongoing fight against COVID-19.
Despite the reduced intensity of the pandemic compared to previous years, hospitals and healthcare workers in some regions are still feeling the strain. Experts report that many hospitals have had to reallocate resources or keep COVID-19 protocols in place due to fluctuating case numbers and severe infections among elderly patients. This ongoing burden is not just a logistical issue—it also highlights the systemic vulnerability that lingers even after the peak pandemic phase.
